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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TWF1
All Species:
39.09
Human Site:
Y68
Identified Species:
78.18
UniProt:
Q12792
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12792
NP_002813.2
350
40283
Y68
L
E
D
K
Q
P
C
Y
I
L
F
R
L
D
S
Chimpanzee
Pan troglodytes
XP_001165727
384
43939
Y102
L
E
D
K
Q
P
C
Y
I
L
F
R
L
D
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543726
350
40067
Y68
L
E
D
K
Q
P
C
Y
I
L
F
R
L
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91YR1
350
40061
Y68
L
E
D
K
Q
P
C
Y
V
L
F
R
L
D
S
Rat
Rattus norvegicus
Q5RJR2
350
40072
Y68
L
E
D
K
Q
P
C
Y
V
L
F
R
L
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508452
357
40765
Y75
L
E
D
K
Q
P
C
Y
I
L
Y
R
L
D
S
Chicken
Gallus gallus
Q5ZM35
349
39817
Y68
L
D
E
Q
Q
P
C
Y
V
L
Y
R
L
D
S
Frog
Xenopus laevis
Q68F50
350
40436
Y68
L
E
D
K
Q
P
C
Y
I
L
Y
R
L
D
S
Zebra Danio
Brachydanio rerio
Q6GMH3
347
39840
L68
P
L
E
P
C
Y
I
L
Y
R
L
D
S
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFM9
343
39052
Y68
L
E
K
D
V
P
C
Y
I
L
Y
R
L
D
A
Honey Bee
Apis mellifera
XP_393653
350
39782
Y68
I
I
E
N
Q
P
A
Y
I
L
Y
R
L
D
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53250
332
37052
K68
E
P
L
Y
I
F
Y
K
P
E
G
L
D
K
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.6
N.A.
97.7
N.A.
94.8
94.5
N.A.
89.9
66.8
79.7
63.1
N.A.
48.2
53.1
N.A.
N.A.
Protein Similarity:
100
90.6
N.A.
99.1
N.A.
97.7
97.4
N.A.
96.3
86.8
91.1
82.5
N.A.
72.2
74
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
93.3
66.6
93.3
0
N.A.
66.6
53.3
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
100
13.3
N.A.
80
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
9
0
75
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
59
9
0
0
0
0
0
0
0
9
9
84
0
% D
% Glu:
9
67
25
0
0
0
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
42
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
9
0
0
9
0
9
0
59
0
0
0
0
0
0
% I
% Lys:
0
0
9
59
0
0
0
9
0
0
0
0
0
17
0
% K
% Leu:
75
9
9
0
0
0
0
9
0
84
9
9
84
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
9
9
0
9
0
84
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
75
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
84
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
67
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% T
% Val:
0
0
0
0
9
0
0
0
25
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
9
9
84
9
0
42
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _